BMSEED

MicroElectrode Array Stretching Stimulating und Recording Equipment (MEASSuRE)
3 Methods – 1 Tool
(Cell Stretching, Imaging, Electrophysiology)

In Vitro Research Without Sacrificing Relevance

Cell Stretching

Radial, uniaxial or customized strain fields.

One fast impulse stretch or cyclical stretch up to 50% strain at strain rates of up to 80/s.

Any stretch pattern.

High reproducibility.

Imaging

Before, during and after stretching up to 2,000 frames per second at 2MP resolution.

Easy-to-use software to independently measure tissue strain.

Electrophysiology

Electrodes stretch with the cells/tissue.

Recording/stimulation before, during, and after stretching

Comparison of pre and post stretch electrophysiological activity (normalization).

Soft microelectrode arrays (MEAs) on elastomeric silicone substrates.

Standard microelectrode arrays (MEAs) on rigid substrates available.

3 Systems available

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MEASSuRE-Mini

1. Mechanics Module: strain rate up to 1/s, strain up to 20 %

2. Imaging Module: frame rate: 150 fps

3. Electrophysiology Module: 2x60 channels

Applications: Physiological Cell Stretching

• Tissue engineering, regenerative medicine

• Organ-on-a-Chip, pre-clinical drug development
• Mechanobiology

further information about MEASSuRE-Mini (PDF)

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MEASSuRE-Premium

1. Mechanics Module: strain rate up to 50/s, strain up to 50 %

2. Imaging Module: frame rate: 2,000 fps

3. Electrophysiology Module: 2x60 channels

Applications: Pathological Cell Stretching

• Traumatic brain injury and repeated concussions

• Spinal cord injury

• Neurodegenerative diseases

• Muscle injuries

further information about MEASSuRE-Premium (PDF)

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MEASSuRE-X

1. Mechanics Module: strain rate up to 80/s, strain up to 50 %

2. Imaging Module: frame rate: 2,000 fps

3. Electrophysiology Module: 2x60 channels

Applications: Pathological Cell Stretching

• Traumatic brain injury and repeated concussions

• Spinal cord injury

• Neurodegenerative diseases

• Muscle injuries

further information about MEASSuRE-X (PDF)

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Accurate Data

Simulate the natural environment

of cells to generate more relevant data.

Efficient Workflow

Replicate multiple techniques with one MEASSuRE unit to save time, money, and research animals.

Unrivaled Results

Better prediction of clinical results by eliminating drug candidates early and reduce failure rate in clinical trials.

Individual Modules of MEASSuRE

Each module is also available as a stand-alone

Electrophysiology Module

120 channel controller
60 channel recording and stimulation (can be upgraded to 120 channels)
Compatible with stretchable and glass MEAs
Significantly lower cost compared to the competitive systems

further information about MEASSuRE (PDF)

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Mechanics Module

3 cell stretching models available for different applications: neurodegenerative diseases, neurotrauma, tissue engineering, drug screening
Variable strain rates
Various strain profiles available (radial, linear, customized)
Customer configurations possible
Use in an incubator
Imaging and Electrophysiology Modules can be added

further information about MEASSuRE (PDF)

to contact form

Mechanics and Imaging Module

3 cell stretching models available with variable strain rates and strain profiles available (radial, linear, customized)
Optical imaging of live cells during stretching motion
High frame rate and resolution
Customer configurations possible
Fluorescent imaging possible
Electrophysiology Module can be added to complete the MEASSuRE system