Automated Tissue Dissociation Systems
Single cells or nuclei from solid tissues in minutes
- Singulator™100
- Singulator™200
- Top features of the systems
- NIC+ small sample cartridge
- Minimal Variability. Multiple Applications.
The bench-top Singulator System and its single-use cartridges enable reproducible, rapid and hands-off tissue dissociations into single-cell or nuclei suspensions. Researchers can now easily obtain suspensions of nuclei or high-viability cells for a wide range of single-cell analyses.
further information about Singulator™100 (PDF)
Singulator 200 doubles throughput by having two chambers where separate cartridges can be processed simultaneously. The chambers are independently controlled using the instrument’s touch-screen interface.
further information about Singulator™200 (PDF)
Preserve Precious Tissue Samples
The NIC+ small sample cartridge is ideal for ultrasmall, precious samples of 2-20 mg. Its performance has been demonstrated for as small as 2 mg of tissue for nuclei isolations. It is compatible with all Singulator nuclei protocols. Cartridges are available as bundles with NIR/NSR reagents or as a cartridge pack for use with reagents of your choice.
Ready to preserve your high-value small sample?
| Tissue Type | Process Time | Yield* | Viability* | |
| Cells | Fresh, FFPE** | 20-60 minutes | 4,000 to >600,000/mg | 80-95% |
| Nuclei | Fresh, Frozen, OCT, FFPE** | 6-10 minutes | 3,000 to >1,000,000/mg | N/A |
*Varies depending on tissue types **Dissociation of deparaffinized, rehydrated FFPE slices.
Minimal Variability. Multiple Applications.
Ideal for genomics, cell biology and other ‘omics applications, including scRNA-Seq, snRNA-Seq, ATAC-Seq, CITE-Seq, FACS, and immuno-oncology. S2 Genomics provides a selection of pre-set protocols and pre-formulated reagents for cell isolations for an expanding set of mouse, rat, and human tissues, including tumors. See the wide range of tissues and organisms demonstrated on the Singulator 100 System here.
