ECIS® Z-Theta                                                  ECIS® TEER Z                                                  ECIS® 8-well Transfilter Array

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ECIS^® Z-Theta

• Complex impedance analyser

• ECIS^® (Electric Cell-substrate Impedance Sensing) quantifies morphology changes in the sub-nanometer to micrometer ranges.

• Small altering currents are applied across an electron pattern at the bottom of the array which results in a potential across the electrodes being measured by the system. Cells act as insulators increasing the impedance.

• Stimulating cells to change their function alter the impedance which can be detected by the system.

• The instrument can use a range of AC-frequencies from 100 to 100 kHz and complex impedance measurement to determine different cell morphology parameters including barrier function, close contacts, and membrane capacitance.

• 16- or 96-well station for use with 8-well or 96-well arrays

• Station is designed to put in an incubator for optimal cell growth. Incubators are also available from Dunn Labortechnik.

• Optional 8-well transfilter array station available (see below)

• Laptop (WIN 11)

• Software for data acquisition and analysis

ECIS® TEER Z

Continuous, Real-time TEER Measurement System:

• Experience seamless and repeatable label-free

        automated transepithelial electrical resistance (TEER)

        measurements, allowing you to electrically track cell

        layers in real-time.

• TEER in 24- or 96-well format

• TEER monitored under standard cell incubation

• Non-invasive measurement

• Read 96 wells in under 5 minutes

• Uses Millipore^® or Corning^® cell-culture insert plates

Specifications:

• Reads 24- or 96-well filter plates
• Medical-grade stainless steel electrode dipping pins
• 75 Hz sinusoidal excitation
• Power: < 2 watts, 12 V dc
• Station: 30 x 13 x 25 cm
• Controller: 48.3 x 43.2 x 21.6 cm
• Windows PC with ECIS^® Software

User Friendly Software:

• TEER values vs. time graph
• Click-button initiation
• Colour-coded well mapping
• Stores values without cells (flat-fielding)
• Group average and compare data
• Statistical error bars
• Data output in CSV or graphical (JPEG, TIFF) 

The ECIS^® TEER Z Cartridge, seamlessly transitions your cell culture plate from the incubator to the cell culture hood while ensuring a sterile environment is maintained. The upper section of the plate features pairs of medical-grade stainless steel dipping pins for easy and precise insertion. 



ECIS^® 8-well Transfilter Array

Benefits:

• Automated TEER measurements under incubated conditions
• Continuous monitoring
• Uses standard 24-well cell culture inserts
• Non-invasive and label-free
  

The ECIS^® 8-well Transfilter Array (8wTFA) allows researchers to measure transepithelial electrical resistance (TEER) on standard cell culture 24-well inserts using Electric Cell-substrate Impedance Sensing (ECIS^®). The 8wTFA can be used with the ECIS^® Z-Theta 16-well station (see above) and can monitor TEER continuously in real-time without having to remove the cells from the incubator. 

09/2024