Product Information - Equipment and Accessories

Please click here for an overview of biomechanical and
cytomechanical
applications using the Flexcell® equipment.
 

   

Flexcell® Tension System (FX-5000T)

  • Apply equibiaxial or uniaxial tension to cells
    in 2D or 3D culture.
  • Computerized, vacuum-operated instrument that applies a defined controlled, static or variable duration cyclic tension to cells growing in vitro.
  • Utilizes regulated vacuum to deform cells cultured on flexible-bottomed culture plates.
  • Simulate in vivo tissue strains and frequencies in cells from muscle, lung, heart, blood vessels, skin, tendon, ligament, cartilage, and bone.

further information

 

 

 

Flexcell® Tissue Train® System (FX-5000TT)

  • 3D cell culture in a gel matrix with or without cyclic uniaxial tension.
  • Stand-alone culture system to create 3D geometries for cell culture in a matrix gel or allows the cells to build a self-assembled matrix that connects to the anchors in a Tissue Train® culture plate.
  • Utilizes regulated vacuum to deform cells cultured on flexible-bottomed culture plates.
  • Simulate in vivo tissue strains and frequencies in cells from muscle, lung, heart, blood vessels, skin, tendon, ligament, cartilage, and bone.

further information

 

 

 

 

Flexcell® Compression System (FX-5000C)

  • Apply cyclic or static compression to cells in
    3D culture.
  • Computerized, pressure-operated instrument that applies a defined controlled, static or variable duration cyclic compression to cells growing in vitro.
  • Utilizes regulated air pressure to deflect BioPress™ culture plates compressing a tissue sample or a 3D culture between a piston and a stationary platen.
  • Simulate in vivo tissue forces and frequencies in cells from muscle, lung, heart, blood vessels, skin, tendon, ligament, cartilage, and bone.

further information

 

 

 

FlexLink® for Tension or Compression
(FX-5000TFL and FX-5000CFL)

  • Upgrade your existing FX-5000T or FX-5000C with a second controller that links with an FX-5000™ system computer allowing the user to simultaneously operate two different regimens on two different baseplates.
  • Expand the application area of your FX-5000T system with the possibility to apply Compression tests by adding a Compression FlexLink® FX-5000CFL.
  • Expand the application area of your FX-5000C system with the possibility to apply Tension tests by adding a Tension FlexLink® FX-5000TFL.

further information

 

 

 


24-Well HT Baseplate Kit with Cell Seeders™

Flexcell® Baseplate Kits

  • Expand the application areas of your Tension or Tissue Train® System
  • Following Baseplate Kits are available:
    - BioFlex
    ® Baseplate Kit to apply equibiaxial
      strain to 2D cell cultures (using the BioFlex
    ®
      culture plates) or to 3D constructs (using the   Tissue Train
    ® Circular Foam culture plates).
    - Tissue Train
    ® Baseplate Kit to apply uniaxial
      strain to 3D cell cultures in Tissue Train
    ®
      culture plates or to monolayer cell cultures in
      UniFlex
    ® culture plates.
    - UniFlex
    ® Baseplate Kit to apply uniaxial strain
      to cells cultured in monolayer in UniFlex
    ®
      culture plates.
    - 24-Well HT Baseplate Kit for high throughput
      strain tests of cells cultured in Flexcell's
    ®
      24-well HT BioFlex
    ® culture plates, with
      Cell Seeders™ to place cells in the central
      region of the wells.

further information

 

 

 

NEW!  Transwell® Holder
Transwell
® is a registered trademark of Corning® Inc.

  • Holds Transwells® to allow for cell migration and co-culture assays to be performed in Flexcell® culture plates.
  • Analyze cell migration in response to strain.
  • Available for 6- and 24-well Flexcell® culture plates.

further information

 

 

 

FlexStop™ (BFS-3000)

  • Use a FlexStop™ to block stretching.
  • Reusable valved rubber stopper that inserts into the underside of a BioFlex® culture plate well to prevent vacuum-induced deformation.
  • Provides a convenient negative control when testing mechanical load effects on cells in the same BioFlex® culture plate.
  • Designed to work in conjunction with the BioFlex® culture plates and BioFlex® Loading Stations™.
  • Also works with Tissue Train® and UniFlex® culture plates.

further information

 

 

 

Flex Jr. Tension System

  • Apply equibiaxial or uniaxial tension to cells in Flexcell's® microscopy devices
    (microscopy devices sold separately).
  • Computerized, vacuum-operated system that applies a defined controlled, static or variable duraction cyclic tension to cells in the microscopy devices StagerFlexer® , StageFlexer Jr.®  and Flex Flow™.

further information

 

 

 

Streamer® Shear Stress Device (STR-4000)

  • Apply fluid shear stress to cells with laminar, pulsatile or oscillating flow.
  • Parallel-plate flow system to investigate fluid-induced shear stress to cells grown in a monolayer.
  • Includes a six-chamber laminar flow device and can be used to apply laminar, pulsatile*, or oscillating* flow to cells cultured on special matrix coated PTFE rimmed culture slips®.
    (*if used with Osci-Flow
    ® , see below)
  • Regulation of shear stress from 0 - 35 dynes/cm2 by computer controlled peristaltic pump.

further information

 

 

 

Osci-Flow® Flow Controller (STR-4000-OFS)

  • Provides regulated oscillatory and pulsatile flow control via computer controlled action.
  • Minimizes flow response lag by eliminating inertial effects of decelerating and accelerating pumps and motors.
  • Reverses fluid flow instantaneously.
  • Works with Streamer® and FlexFlow™ shear stress devices.

further information

 

 

 

StageFlexer® Microscopy Device (SF-3000)

  • A single-well embodiment of a BioFlex® culture plate well designed to strain cells in monolayer while observing the cellular activity with an upright microscope in real-time.
  • Device can be used with Flexcell's® Tension, Tissue Train®, or Flex Jr. Tension systems that allow the control of strain frequency, amplitude, waveform, and cycles (or time period).

further information

 

 

StageFlexer® Jr. Microscopy Device (SF-4000)

  • Microscopy device for membranes removed from BioFlex®, UniFlex®, or Tissue Train® plates.
  • Designed to strain cells in monolayer while observing the cellular activity with an upright microscope in real-time.
  • Device can be used with Flexcell's® Tension, Tissue Train®, or Flex Jr. Tension systems that allow the control of strain frequency, amplitude, waveform, and cycles (or time period).

further information

 

 

 

FlexFlow™ Shear Stress Device (FF-3000)
Temporary special price offer - subject to prior sale.
Please contact us for further information.

  • Parallel plate laminar flow device designed to apply fluid shear stress and/or cyclic strain to cells in culture while providing a means for viewing cell activity under an upright microscope in real-time.
  • Strain cells using the Flexcell's® Tension, Tissue Train®, or Flex Jr. Tension systems before, during or after applying shear stress.
  • Uses a computer controlled peristaltic pump to regulate shear stress from 0 - 35 dynes/cm2.

further information

 

 

 

StagePresser™ Microscopy Device (SP-3000)

  • A single-well embodiment of the Compression apparatus designed to compress a single tissue sample or cells in a 3D culture while viewing the cellular activity under an upright microscope.
  • Works with the Compression System.

further information

 

 

 

  

ScanFlex™ Scanning Device

  • Automated scanning device with area measurement software XyFlex™.
  • Can be used in conjunction with the Tissue Train® system to determine the compaction kinetics (change in area) of 3D cell seeded-gels.
  • Scans four 6-well or 24-well Flexcell® culture plates.
  • Measure gel compaction in 3D bioartificial tissues.
  • Automated repetitive scanning process.

further information

 

Also available: Flexcell Culture Plates and Slides.